Can I just say that you have a great site! I’m a regular reader, and think that I have a question for you that may be interesting. I’ve searched through your archives and haven’t found a similar question, but if I have missed it, please accept my apologies.
Recently I have had a look through the FDA trial reports on finasteride, but cannot find any information on the body sizes and characteristics of the patients used in the study. Are such data available? (Histograms, Mean/median, SD, etc).
Whilst I am assuming that the effective dose of finasteride for treating MPB is related to body size, and that the occurrence of side effects increases with relative dose, could there be a case for smaller dosages being suitable for people smaller than the people used in the FDA study – Asians and orientals for example? As this blog is international, I feel that we “vertically challenged” of the rest of the world need to know! :)
I passed your question to Merck and I just got an answer. Essentially, the only thing that was studied was the average dose that is effective and it was not related to a person’s weight. Body size was not studied.