hello doctor rassman
there was a study done where finasteride upregulates adrogen receptors in the prostate. here is the link– PubMed
is it possible that a user who takes finasteride for hairloss can have an upregulation of androgen receptors at scalp level? therefore causing more hairloss while on propecia? or propecia not working at all?
I am not a biochemist to give you a clear answer on how this study relates to hair loss. Of note, this was a very limited study in 47 cases in a cell line study.
The big picture here is that people take Propecia for the treatment of hair loss, and the studies of this drug have shown effectiveness for this. The research does not show that it produces hair loss.