I think despite how much you caution your readers about the dangers of going with Avodart, as it is not approved by FDA, I think deep down you must understand how desperation will drive us to at least consider it.
With that in mind, it only just occurred to me…a while back, you mentioned that it’s possible, based on your educated guess, that only a monthly dose of Avodart would be necessary since the half-life was so long (again I emphasize for the readers that it was just an educated guess).
For those of us willing to take the risk, wouldn’t this risk be minimized by only taking it once a month? I’m thinking – why not continue to take Propecia daily, in addition to Avodart once a month? Surely, while risky, it’s a safer option for those of us who really aren’t responding to Propecia that well.
I don’t think that I said that Avodart (dutasteride) was a drug with risk, I just said that it was not approved by the FDA for treating hair loss. Clearly the drug is approved for prostate problems and is considered safe. The half life of this drug is 5 weeks, but it reaches only to 65% of its steady state level after 1 month and 90% after 3 months with daily doses of the medication. Once a month should not (in theory) create therapeutic levels in serum, but that doesn’t create it for prostate applications. Although your analysis is reasonable, knowing what dose to use is ‘hokey’. I also just don’t know how to judge if it is working, nor do I know what the best dose is, what the best frequency to take it, or whether to up the dose if it doesn’t work.